Age and gender differences in the clustering of metabolic syndrome combinations: A prospective cohort research from the Kerman Coronary Artery Disease Risk Study (KERCADRS)

Abstract

BackgroundThe features of metabolic syndrome (MetS) and its components are now different in Iran compared to western countries. AimsThe aim of this study was to provide estimates of the prevalence of the different MetS combinations in younger and older men and women in Iran. MethodsA detailed interview regarding social demographics risk profile, and components of MetS was administered according to the Kerman Coronary Artery Disease Risk Study (KERCADRS) as population-based, epidemiological research among a cohort of 6000 individuals that residence in Kerman city. ResultsThe overall prevalence of MetS was 25.2% in men and 42.5% in women considering the International Diabetes Federation (IDF) criteria and 31.0% in men and 38.0% in women when the National Cholesterol Education Program (NCEP) definition was applied. MetS was significantly more prevalent in females, using both definitions. The prevalence of MetS increased with age in both gender when both syndrome criteria were considered. The prevalence of different combinations of the syndrome by both definitions peaked in the age range 51–60 years among both men and women. The appearance of each component was observed earlier in women than men. ConclusionThe prevalence of the MetS in the State of Kerman, a great province in the south-east of Iran is estimated as 35.0%, higher than in most developed countries and some other Middle-East regions, with generally higher prevalence rates for women. The prevalence of MetS increases with age in both genders with earlier appearance in men.