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Abstract
PURPOSE: Pulmonary hypertension (PHTN) is a known risk factor for morbidity and mortality in patients with COPD. Identifying COPD patients at risk for developing PHTN may improve outcomes. Hypoxic pulmonary vasoconstriction, destruction of alveolar capillaries and hyperinflation are proposed mechanisms of PHTN in COPD, but only a few studies have evaluated the ability of pulmonary function testing to identify PHTN in these patients.
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