Agar Gel Electrophoresis in Neurology.

Abstract

The title of this book belies its content because a significant portion of it is devoted to paper electrophoresis in neurology. The author correlates the spinal fluid protein patterns obtained with paper electrophoresis in over 500 normal and pathological cases with that obtained with agar gel electrophoresis in more than 800 samples. The results favorably support the opinion of the author that the newer technique of agar gel electrophoresis is superior to that of paper electrophoresis. Approximately 20 different protein bands are seen in the spinal fluid with agar gel while only 6-7 bands are demonstrable with paper electrophoresis. However, in spite of greater resolubility with agar gel, clinically the method adds little additional information to that obtainable with paper electrophoresis. The volume also contains a brief discussion on the applicability of agar gel electrophoresis in the study of soluble brain proteins. The monograph is a valuable contribution to the