Ag(I), Cu(II), and Cd(II) sulfacetamide complexes: Synthesis, spectral, thermal study, and antimicrobial activity assessment

Abstract

Sulfacetamide complexes of Ag(I), Cu(II), and Cd(II) were synthesized and characterized by the elemental analyses and IR and 1H NMR spectra. Structural assessment revealed two modes of coordination in the sulfacetamide complexes, showing that sulfacetamide reacts as a bidentate ligand and coordinates to Ag(I) and Cd(II) through the amido and sulfonyl oxygens and to Cu(II) through the NH2 nitrogen. Molar conductance measurements in DMSO showed that both the complexes are nonelectrolytes in nature, which allowed they to be assigned the formulas [Ag(SAM-Na)(NO3)H2O)]·3H2O, [Cu(SAM-Na)2(Cl)2], and [Cd(SAM-Na)(Cl)2]·10H2O. The kinetic and thermodynamic parameters of the thermal decomposition reactions of the complexes were estimated from the TG/DTG curves by the Coats–Redfern and Horowitz–Metzeger methods. The surface morphology of sulfacetamide complexes was scanned using X-ray powder diffraction (XRD) and scanning electron microscope (SEM) analyses.