Abstract
Flow cytometric DNA analysis using formalin-fixed, paraffin-embedded tissues were performed on nine cases of African endemic-type Kaposi's sarcoma (KS). Histologically, these cases were classified into the following three types; granulation tissuelike (one case), angioma/angiosarcoma-like (four cases) and spindle cell (four cases). Although these three types showed a variety of cellularity and cellular atypism, there were no fundamental differences in the view point of proliferation of spindle cell. Mitotic figures were not prominent. All cases were exclusively diploid and lacked an aneuploid population by flow cytometric measurement of DNA content. These results suggest that African endemic-type KS is a less aggressive disease rather than a malignant neoplasm.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
