Abstract
Burkitt's lymphoma is an aggressive lymphoma that is common in sub-Saharan Africa but rare elsewhere.1 First described in African children by Denis Burkitt,2 the uneven distribution of Burkitt's lymphoma attracted worldwide interest and led to seminal discoveries. For example, Epstein-Barr virus, the first virus to be associated with a human cancer, chromosomal translocations, and elucidation of molecular aberrations in MYC, Rb, and p53 genes—now regarded as central to the biology of cancer—is closely linked to Burkitt's lymphoma.
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