Abstract
Africa Centres for Disease Control and Prevention's framework for antimicrobial resistance control in Africa.
Highlights
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In Africa where many health systems are weak, the likelihood of Antimicrobial resistant (AMR) increasing and the consequences of AMR infections are high, and drug resistance has already been documented for HIV and the pathogens that cause malaria, tuberculosis, typhoid, cholera, meningitis, gonorrhoea, and dysentery.[5]
AMR strains arise naturally due to genetic changes in replicating microorganisms, their emergence is accelerated by inappropriate use of antimicrobial agents in humans, animals, and the environment.[8]
Summary
Africa Centres for Disease Control and Prevention’s framework for antimicrobial resistance control in Africa. AMR strains arise naturally due to genetic changes in replicating microorganisms, their emergence is accelerated by inappropriate use of antimicrobial agents in humans, animals, and the environment.[8] AMR emergence may be amplified by substandard or counterfeit antimicrobials, which impair treatment of existing infections and may select for AMR strains.[9] Transmission of AMR is accelerated by inadequate infection prevention and control in health care facilities, by contamination of the food supply with AMR bacteria, by impaired access to potable water, and by limitations in public health prevention programmes, including immunisation, sanitation, and sexual health.[10] Globally, drug resistance causes an estimated 700 000 deaths each year, and if current trends continue, AMR could result in over 10 million deaths per year and over $100 trillion (United States dollars) in lost output globally by 2050.11. After consultation with subject matter experts in Africa and globally, Africa CDC developed a framework that has four objectives: (1) improve surveillance of AMR
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