Abstract
The aim of the study was to reveal clinical and dynamic characteristics of affective disorders (AD) in comorbidity with alcohol addiction (AA). Materials and methods. 65 patients with affective disorders [22 women (34%) and 43 men (66%)] were examined. The main group included 34 patients aged 44.5 [36.0; 51.5] with affective disorders and comorbid alcohol addiction The comparison group included 31 patients aged 45 years [32; 52] with affective disorders without comorbid narcological pathology. Compared groups were matched by sex, age and nosological structure (p > 0.05). The following methods were used in the study: clinical and psychopathological, clinical follow-up, psychometric, statistical, as well as these psychometric scales: Clinical Global Impression (CGI), Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale (HARS), Social Adaptation Self-evaluation Scale (SASS). Results. The comparative assessment of clinical and dynamic characteristics of affective disorders and social adaptation level was conducted. Chronology of occurrence of comorbid affective disorders and alcohol addiction was analyzed. Conclusion. Addition of alcohol addiction to affective disorders worsens the clinical and dynamic indices and social adaptation level of patients.
Highlights
Materials and methods. 65 patients with affective disorders [22 women (34%) and 43 men (66%)] were examined
Compared groups were matched by sex, age and nosological structure (p > 0.05)
The following methods were used in the study: clinical and psychopathological, clinical follow-up, psychometric, statistical, as well as these psychometric scales: Clinical Global Impression (CGI), Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale (HARS), Social Adaptation Self-evaluation Scale (SASS)
Summary
Васильева С.Н.1, Симуткин Г.Г.1, Счастный Е.Д.1, Лебедева Е.В.1, Бохан Н.А.1, 2, 3. Цель исследования – выявление клинико-динамических характеристик аффективных расстройств (АР) при их коморбидности с алкогольной зависимостью (АЗ). Основная группа – 34 пациента с аффективными расстройствами и коморбидной алкогольной зависимостью в возрасте 44,5 лет [36,0; 51,5]. Проведена сравнительная оценка клинико-динамических характеристик аффективных расстройств и уровня социальной адаптации. Присоединение алкогольной зависимости к аффективным расстройствам ухудшает их клинико-динамические показатели и уровень социальной адаптации пациентов. Исследование выполнено при поддержке гранта РНФ 19-15-00023 «Клинические особенности и поиск потенциальных биомаркеров коморбидности алкоголизма и аффективных расстройств». Для цитирования: Васильева С.Н., Симуткин Г.Г., Счастный Е.Д. Аффективные расстройства при коморбидности с алкогольной зависимостью: клинико-динамические особенности, уровень социальной адаптации больных. Аффективные расстройства при коморбидности с алкогольной зависимостью. Vasilieva S.N.1, Simutkin G.G.1, Schastnyy E.D.1, Lebedeva E.V.1, Bokhan N.А.1, 2, 3
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