Afectación renal en las enfermedades autoinmunes sistémicas y en las vasculitis

Abstract

Systemic autoimmune diseases are a heterogeneous group of diseases sharing the same etiology, a disorder of immunological system that forms specific antibodies, but showing different clinical manifestation and diagnosis. Usually, the end-organ of these disorders is the kidney. Histologically is characterized by tissue damage caused by the deposition of immunocomplexes and inflammation resulting in glomerulonephritis. Renal impairment in systemic lupus erythematosus, vasculitis, secondary amyloidosis, scleroderma, sarcoidosis, Sjögren's syndrome and nephropathy in IgG4-related systemic disease will be reviewed in current update.