Abstract

We thank Professor Lee for his interest in our recent LUX-Lung 7 publication that assessed afatinib versus gefitinib in patients with epidermal growth factor receptor ( EGFR ) mutation-positive non-small cell lung cancer (NSCLC) (1). We agree that, in an ideal world, afatinib and gefitinib would have been compared in a Phase III trial with a formal hypothesis. However, given the lack of data available at the conception of LUX-Lung 7 (2010‒2011), we made the pragmatic decision to undertake an exploratory Phase IIb trial.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.