Abstract
Nowadays, the effectiveness of inhalation drug therapy during non-invasive ventilation (NIV) has been proved. The delivery of aerosol drugs during non-invasive ventilation depends on numerous factors, such as the choice of inhalation equipment and a mask, position of the leak port and position of the device in the respirator settings. Innovations in the field of inhalation therapy resulted in the development new devices able to optimize pulmonary deposition and reduce the time of inhalation therapy. Compared to standard jet nebulizers, mesh nebulizers can deliver the 4 fold higher dose of the drug to the patient's airways. Further research is needed in order to investigate the opportunities of aerosol therapy during high-flow oxygen therapy by means of nasal cannulae.
Highlights
Nowadays, the effectiveness of inhalation drug therapy during non-invasive ventilation (NIV) has been proved
The delivery of aerosol drugs during non-invasive ventilation depends on numerous factors, such as the choice of inhalation equipment and a mask, position of the leak port and position of the device in the respirator settings
Innovations in the field of inhalation therapy resulted in the development new devices able to optimize pulmonary deposition and reduce the time of inhalation therapy
Summary
К настоящему времени получены доказательства эффективности ингаляционной лекарственной терапии во время неинвазивной вентиляции легких (НВЛ). Н. Аэрозольная терапия во время неинвазивной вентиляции легких // Вестник анестезиологии и реаниматологии. The delivery of aerosol drugs during non-invasive ventilation depends on numerous factors, such as the choice of inhalation equipment and a mask, position of the leak port and position of the device in the respirator settings. С учетом возрастающего числа пациентов, получающих респираторную поддержку с помощью НВЛ в стационаре и в домашних условиях, а также с увеличением количества аэрозольных препаратов все чаще возникают вопросы о методах аэрозольной терапии во время проведения НВЛ. В другом недавнем проспективном исследовании также было подтверждено частое использование ингаляционных препаратов во время НВЛ, однако аэрозольная терапия преимущественно проводилась в период между сеансами респираторной поддержки [16]. В данной статье на основе доступных исследований in vitro и клинических исследований обсуждаются методы аэрозольной терапии во время НВЛ, а также ВПКТ
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