Abstract

Background:Chronic obstructive pulmonary disease (COPD) appears to be associated with low bone mineral density (BMD) due to long-term use of corticosteroids as a result patients with COPD are at risk for osteoporosis-related fractures and worsening pulmonary function.Objective:The present study aimed to measure the effects of treadmill walking exercises on bone mineral status in patients with COPD.Methods:Sixty patients with moderate COPD of both sexes, their age ranged from 45 to 58 years. Subjects were divided into two equal groups: training group (group A) received aerobic exercise training on treadmill for six months, where the second group (B) was considered as a control group who received no exercise training. The program consisted of three sessions per week for six months.Results:The results of this study indicated a significant increase in BMD of the lumbar spine & the radius and serum calcium & significant reduction in parathyroid hormone in group (A), while these changes were not significant in group (B).Also; there was a significant difference between both groups at the end of the study.Conclusion:Treadmill walking exercise training is an effective treatment policy to improve bone mineral status in patients with COPD.

Highlights

  • Chronic obstructive pulmonary disease (COPD) is a prevalent global disorder [1], associated with high risk of osteoporosis in addition to the high economic burden of the disease medical care [2,3,4]

  • Diagnosis and staging of COPD was according to GOLD criteria [35].Peripheral blood was collected in the morning under fasting conditions, and the plasma concentrations of calcium and parathyroid hormone (PTH) were measured by routine assays

  • The results of this study indicated a significant increase in bone mineral density (BMD) of the lumbar spine & the radius and serum calcium & significant reduction in parathyroid hormone in group (A), while these changes were not significant in group (B) (Table 2 and3)

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Summary

Introduction

Chronic obstructive pulmonary disease (COPD) is a prevalent global disorder [1], associated with high risk of osteoporosis in addition to the high economic burden of the disease medical care [2,3,4]. Chronic Obstructive Pulmonary Disease (COPD) is a progressive and partially reversible disorder [8] due to its pulmonary and extra-pulmonary manifestations [9, 10] one of these extra-pulmonary manifestations which affects patients with COPD more than health subjects by two to five folds (1113), the decline in bone mineral density (BMD) was found to be correlated with the decline in the lung functions [14]. Chronic obstructive pulmonary disease (COPD) appears to be associated with low bone mineral density (BMD) due to long-term use of corticosteroids as a result patients with COPD are at risk for osteoporosis-related fractures and worsening pulmonary function. Conclusion: Treadmill walking exercise training is an effective treatment policy to improve bone mineral status in patients with COPD.

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