Abstract
Five medications are approved for treating obese and overweight patients: orlistat (Xenical; Alli), lorcaserin (Belviq), naltrexone-bupropion (Contrave), phentermine-topiramate (Qsymia), and liraglutide (Saxenda). For this meta-analysis, researchers identified 28 randomized trials that involved 29,018 patients (median age, 46; median baseline body-mass index, 36.1 kg/m2); in all trials, one or more of the five …
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