Abstract
The ongoing Corona Virus Disease (COVID-19) is a pandemic disease adversely affecting health and also incurred severe financial losses globally. Vaccination is the important preventing measure to combat COVID-19 infection. Vaccine hesitancy due to the fear of side effects is a major drawback for successful implementation of immunization programs. Extensive studies on safety of COVID-19 vaccination are much needed to address this problem. The current study aims at evaluating adverse effects following vaccination against COVID-19 infection. A total of 584 healthcare personnel who received either COVISHIELD or COVAXIN were included in the study. The adverse effects after first and second dose of vaccines in different time intervals (<24hrs, 24-48hrs, 3-7days) were recorded by using World Health Organization (WHO) based questionnaire. Among the participants, 360 received COVISHIELD and 220 received COVAXIN vaccine. Majority of the subjects experienced side effects within first 24hrs of first dose (COVISHIELD 84%, COVAXIN 90%) and also of second dose (COVISHIELD 73%, COVAXIN 89%). Side effects like general weakness, headache, fever, chills and myalgia were the most common side effects observed with both vaccines.
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