Adverse Drug Reactions as A Cause of Hospital Admission Hospital Universitario De La Princesa – Madrid

Abstract

ObjectiveTo detect the incidence of adverse drug reactions as cause of admission to the Hospital Universitario de la Princesa in Madrid.Materials and MethodsTransversal study, between June to December of May 2014. An electronic medical records review of patients admitted through the emergency was performed. We assessed whether the cause of admission was secondary to medication use. Causality was assessed according to the Naranjo algorithm and WHO criteria.ResultsThere were 3917 admissions in that period, with a mean age of 77 years. In a preliminary analysis, we found 222 (being the sample size 195 subjects, 45.1% male and 54.9 female) the most representative: NSAID gastrointestinal bleeding/gastrointestinal bleeding on antiplatelet/anticoagulated patient: 37 (16.7%), Renal Insufficiency: 21 (9.5%), hyponatremia: 21 (9.5%), intracranial haemorrhage on antiplatelet/anticoagulated patient: 31 (14%), serotoninergic syndrome: 2 (0.9%), neutropenic fever: 18 (8.1%),diarrhea caused by clostridium difficile: 3 (1.4%) and four cases of medication error.ConclusionsThe incidence of admission by adverse reactions is similar to other studies performed in other countries, around 5.7%, being the most frequent gastrointestinal bleeding associated with antiplatelet drugs or oral anticoagulants. ObjectiveTo detect the incidence of adverse drug reactions as cause of admission to the Hospital Universitario de la Princesa in Madrid. To detect the incidence of adverse drug reactions as cause of admission to the Hospital Universitario de la Princesa in Madrid. Materials and MethodsTransversal study, between June to December of May 2014. An electronic medical records review of patients admitted through the emergency was performed. We assessed whether the cause of admission was secondary to medication use. Causality was assessed according to the Naranjo algorithm and WHO criteria. Transversal study, between June to December of May 2014. An electronic medical records review of patients admitted through the emergency was performed. We assessed whether the cause of admission was secondary to medication use. Causality was assessed according to the Naranjo algorithm and WHO criteria. ResultsThere were 3917 admissions in that period, with a mean age of 77 years. In a preliminary analysis, we found 222 (being the sample size 195 subjects, 45.1% male and 54.9 female) the most representative: NSAID gastrointestinal bleeding/gastrointestinal bleeding on antiplatelet/anticoagulated patient: 37 (16.7%), Renal Insufficiency: 21 (9.5%), hyponatremia: 21 (9.5%), intracranial haemorrhage on antiplatelet/anticoagulated patient: 31 (14%), serotoninergic syndrome: 2 (0.9%), neutropenic fever: 18 (8.1%),diarrhea caused by clostridium difficile: 3 (1.4%) and four cases of medication error. There were 3917 admissions in that period, with a mean age of 77 years. In a preliminary analysis, we found 222 (being the sample size 195 subjects, 45.1% male and 54.9 female) the most representative: NSAID gastrointestinal bleeding/gastrointestinal bleeding on antiplatelet/anticoagulated patient: 37 (16.7%), Renal Insufficiency: 21 (9.5%), hyponatremia: 21 (9.5%), intracranial haemorrhage on antiplatelet/anticoagulated patient: 31 (14%), serotoninergic syndrome: 2 (0.9%), neutropenic fever: 18 (8.1%),diarrhea caused by clostridium difficile: 3 (1.4%) and four cases of medication error. ConclusionsThe incidence of admission by adverse reactions is similar to other studies performed in other countries, around 5.7%, being the most frequent gastrointestinal bleeding associated with antiplatelet drugs or oral anticoagulants. The incidence of admission by adverse reactions is similar to other studies performed in other countries, around 5.7%, being the most frequent gastrointestinal bleeding associated with antiplatelet drugs or oral anticoagulants.