Advantages of Metformin Therapy for Diabetic Foot Ulcer Prevention and Mitigation

Abstract

Introduction: Diabetes foot is one of the most common complications of diabetes. Metformin treatment may aid in lowering the prevalence of diabetic foot ulcers in diabetic patients. Study objectives: The purpose of this study was to look into the prevalence of diabetic foot ulcers among diabetic patients attending out-patient, as well as the impact of metformin treatment on the development of diabetic foot ulcers. Methodology: To collect data from diabetic patients' files, a retrospective design was used. Demographic variables such as gender and age were included in the study, as well as clinical variables such as diabetes duration, metformin treatment, and diabetic foot ulcer status. Data was gathered and entered into SPSS version 20 for analysis. Descriptive features of statistical analysis included frequency, percentage, mean, and standard deviation. Various statistical models, such as the Chi-square test, One Way Anova, and Pearson's correlation, were used to investigate the relationship between variables. If p 0.05, the significance was accepted. Results: The study included 62 diabetic patients with an average age of 56.9511.98 years. The males were 33 (53.2%), the duration of diabetes was 7.55.86 years, metformin was prescribed to approximately 66% of patients, the mean metformin dose was 1617.32649.49 mg, and the prevalence of DF was 8.1%. There were no significant relationships between DF and gender or metformin use (p>0.05). Both the One-Way Anova Test and the correlation test revealed that DF was significantly related to DF. Conclusion: The current study found that metformin treatment is significantly associated with metformin dose and could protect diabetic patients from developing DF.