Advantages of immunohistochemistry in the diagnosis of chronic endometritis

Abstract

Currently in Russia there is a high frequency of infertile marriages and spontaneous abortions. One of the main causes of fertility for women is endometrial pathology. Structural and functional deficiency of the endometrium caused by pathological inflammatory processes, naturally leads to disruption of implantation and clinically infertility and prenatal losses. Search for solutions to the treatment of endometrial pathology extremely relevant for the prevention of reproductive health of society. The main causes of endometrial pathology is inadequate hormonal regulation, acute and chronic inflammation (endometritis). For chronic endometritis is often characterized by a long asymptomatic and complexity of initial diagnosis. A special place in the course of chronic endometritis belongs herpes infection. Its prevalence among young population is high enough. Herpes infections can affect almost all organs and systems of the host. Diagnostic approaches to verification of chronic endometritis constantly adapting over the past decades. Today, the diagnosis is based on a comprehensive assessment of a number of clinical, morphological, instrumental data. Particular attention is paid to the verification of chronic endometritis immunohistochemical study of the endometrium. This method allows not only to identify the type of infectious agent, but also to establish a process phase that has a significant role in determining treatment strategy. Special role in identifying immunohistochemical viral etiology of chronic endometritis, because this method can reliably detect the presence of antigens to different viral agents.