Advantages and Disadvantages of Different Insulin Administration Methods for the Treatment of Diabetes

Abstract

The prevalence of diabetes has been on the rise in recent years, with a significant increase in China. 1980 epidemiological data on 300,000 people in 14 provinces and cities across the country showed that the prevalence of diabetes was 0.67%. By 2013, the prevalence had skyrocketed to 10.4%. Subcutaneous injection is the main route of insulin administration, however, patient compliance is poor and there are many adverse effects. This paper analyzes the advantages and disadvantages from both non-injectable and injectable delivery perspectives through a literature review. This paper finds that insulin pumps and insulin needle-free syringes are both good treatments for diabetes, but they are expensive and not easily accessible on a large scale, while oral administration is also a good treatment, but with low bioavailability. This paper provides researchers with new developments and perspectives on the future of insulin delivery and provides patients with a painless and efficient way to administer insulin.