Abstract

Despite effective drug treatment and the widespread use of the BCG vaccine, tuberculosis causes about 1·3 million deaths every year.1 About 3 million cases of tuberculosis remain undiagnosed and continue to spread the disease. Nearly half a million cases of multidrug-resistant tuberculosis are diagnosed worldwide every year and a third of patients with this disease will die because of failure of diagnosis or unavailability of appropriate treatment.1 Drug resistance beyond extensively drug-resistant tuberculosis is increasingly being reported.

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