Abstract

Objective: Despite the vast number of photoplethysmography (PPG) research publications and growing demands for such sensing in Digital and Wearable Health platforms, there appears little published on signal quality expectations for morphological pulse analysis. Aim: to determine a consensus regarding the minimum number of undistorted i.e., diagnostic quality pulses required, as well as a threshold proportion of noisy beats for recording rejection.Approach: Questionnaire distributed to international fellow researchers in skin contact PPG measurements on signal quality expectations and associated factors concerning recording length, expected artifact-free pulses (“diagnostic quality”) in a trace, proportion of trace having artifact to justify excluding/repeating measurements, minimum beats required, and number of respiratory cycles.Main Results: 18 (of 26) PPG researchers responded. Modal range estimates considered a 2-min recording time as target for morphological analysis. Respondents expected a recording to have 86–95% of diagnostic quality pulses, at least 11–20 sequential pulses of diagnostic quality and advocated a 26–50% noise threshold for recording rejection. There were broader responses found for the required number of undistorted beats (although a modal range of 51–60 beats for both finger and toe sites was indicated).Significance: For morphological PPG pulse wave analysis recording acceptability was indicated if <50% of beats have artifact and preferably that a minimum of 50 non-distorted PPG pulses are present (with at least 11–20 sequential) to be of diagnostic quality. Estimates from this knowledge transfer exercise should help inform students and researchers as a guide in standards development for PPG study design.

Highlights

  • Photoplethysmography (PPG) is a vascular optical measurement technique, used to detect blood volume changes in the microvascular bed of target tissue [1]

  • Our study also provides initial recommendations available for other workers in the field of PPG—facilitating knowledge transfer to students and researchers to support the move toward improved standardization in measurement protocol, morphological pulse wave analysis, as well as address the real-world problem of artifact reduction in PPG

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Summary

Introduction

Photoplethysmography (PPG) is a vascular optical measurement technique, used to detect blood volume changes in the microvascular bed of target tissue [1]. Many studies have been conducted investigating various body sites as a single measurement (e.g., single PPG sensor located on a single body site) and multi-site measurements (multiple PPG sensors located across a range of body sites). A range of features of the pulse wave have been studied, including pulse transit time, pulse interval, peakto-peak interval, amplitude, pulse contour, as well as their natural variability [1]. PPG has been utilized in an array of settings, from bedside physiological measurement e.g., heart rate, oxygen saturation, to hypertension assessment, and detailed peripheral vascular assessment [1,2,3,4]. PPG has become a key sensing technology in Digital and Wearable Health devices

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