Advancing interfacial properties of carbon cloth via anodic-induced self-assembly of MOFs film integrated with α-MnO2: A sustainable electrocatalyst sensing acetylcholine

Abstract

The metal organic frameworks (MOFs) with tunable composition, modified structure, and morphologically controlled nanoarchitectures are quite imperative to improve the electrochemical (EC) performances of sensing platforms. Herein, EC control over the fabrication of HKUST-1 (Cu-MOFs) nanocrystals is achieved via anodic-induced electrodeposition approach following the mixing of Cu2+ salt precursor in the vicinity of benzene-1,3,5-tricarboxylate (BTC3−) ligands. The problem of controlled mass transfer and slow dispersal of MOFs is resolved by EC deposition of pyramidal-octagonal MOFs on a highly conductive and flexible carbon substrate (activated carbon cloth, ACC) wrapped with rGO layers (ACC-rGO@Cu(BTC). Further, α-MnO2 is integrated on ACC-rGO@Cu(BTC) to achieve the synergistic effect of ternary structure interfaces. The novel ACC-rGO@Cu(BTC)@MnO2 based flexible electrode exhibits striking EC performance toward non-enzymatic sensing of acetylcholine (ACh) including wide linear range (0.1 µM - 3 mM), lowest detection limit (5 nM, S/N = 3), high selectivity, and long-term stability. Moreover, the developed sensing system has been applied for real-time detection of ACh efflux released from three different cell lines and biological matrices. Our work unlocks a new prospect of precisely structured MOFs with extensive functionalities and scaled-up fabrication methods via selection of nanoscale reaction centers to develop flexible sensing devices.