Abstract
Tick-borne encephalitis (TBE) is a well-known central nervous system (CNS) infection in children.The disease in children is generally milder, although severe illness may occur and even lead to permanent impairment of the quality of life due to neuropsychological sequelae.We review the epidemiological and clinical characteristics of tick-borne encephalitis, and summarise biological and virological aspects that are important for understanding the life-cycle and transmission of the virus.Tick-borne encephalitis virus is a flavivirus that is transmitted by ixodes persulcatus.Tick-borne encephalitis causes acute meningoencephalitis.The serological diagnosis is usually straightforward.No specific treatment for the disease exists, and immunisation is the main preventive measure. Key words: Tick-borne encephalitis virus; Pathogenicity; Virology; Epidemiology; Immunology; Vaccination
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