[Advances on sample pretreatment and analytical method for the analysis heterocyclic amines in meat products]

Abstract

Heterocyclic amines (HAs) are considered as highly potential mutagens and carcinogens in cooked meat products. Efficient sample pretreatment as well as sensitive analytical method is very important for the determination of HAs in complex samples. In this paper, some sample pretreatment methods such as solvent extraction, solid-phase extraction, and solid- phase microextraction as well as analytical methods including liquid chromatography, and liquid chromatography-mass spectrometry are reviewed; The progress of HAs analysis is also prospected. A total of 51 references are cited.