Abstract

Hematopoietic cell transplantation (HSCT) offers the most effective therapy for patients with myclodysplastic syndromes (MDS) who have a human leukocyte antigen (HLA)-matched sibling donors and results have improved progressively over the past decade. For patients without an HLA-matched donor,volunteer unrelated donor(VUD) HSCT, unrelated cord blood allogeneic stem cell transplantation (CBT) and autologous HSCT may be the alternative. In this review the indication of transplantation and the prognostic factors for outcome after HSCT including patient age, timing of transplantation, induction chemotherapy before HSCT, conditioning regimens, source of stem cell were analysed. Key words: Myelodysplastic syndromes; Hematopoietic stem cell trantsplantation

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