Abstract
The occurrence of breast cancer is closely related to genetic factors. BRCA1 and BRCA2, breast cancer susceptibility genes, play important roles in the occurrence and development of breast cancer. The researches on germline mutations in BRCA1 and BRCA2 are of great significance in prevention, diagnosis and treatment of breast cancer. Key words: Breast neoplasms; Genes, BRCA1; Genes, BRCA2; Mutation; Clinical application
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