Abstract
Temporomandibular joint osteoarthritis (TMJOA) is a clinically common chronic degenerative disease of the TMJ. The degeneration of articular cartilage is a sort of typical pathological characteristics; and chondrocytes’ death is the kernel event in cartilaginous degeneration. Programmed cell death (PCD) has become a academic hotspot in the development of TMJ OA. Based on the concept, aetiology, morphological feature, pathogenesis of five well-known PCD including apoptosis, autophagy, pyroptosis, necroptosis and ferroptosis, as well as their recent research progresses on cartilage degeneration, this narrative review was designed and performed.
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