Abstract

溶血尿毒综合征(HUS)是以微血管病性溶血性贫血、急性肾功能衰竭和血小板减少为主要特征的临床综合征.该文综述r国内外关于HUS的治疗方案,目前公认的有效措施包括急性期对于肾功能衰竭的综合治疗、预防并发症的发牛、必要时予血浆置换或血浆输注以及早期透析(血液透析或腹膜透析)等.对于小典型HUS,治疗的重点在于纠正补体调节因子的缺陷.急性期后则应根据不同的临床表现给予相应的治疗,早期限制蛋白质摄入和长期应刚血管紧张素转换酶抑制剂是延缓.肾损害进程、改善预后的主要方法。

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