Abstract

Glioblastoma is the most common primary malignant brain tumor in adults. More than half of newly diagnosed glioblastoma patients are over 65 years old. The current standard treatment for glioblastoma is surgical resection, followed by concurrent chemoradiotherapy. There is no consensus recommendation regarding the best available treatment for glioblastoma in elderly patients due to the individual specificity and tumor heterogeneity. This review discussed the management of glioblastoma in elderly patients including surgery, chemoradiotherapy, and immunotherapy, in order to provide a reference for the development of a reasonable treatment regimen for elderly patients with glioblastoma. Key words: Glioblastoma; Surgical procedures, Operative; Radiotherapy; Chemotherapy; Research progress

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