Abstract
The information from the tick cattle microbiota suggests that the microbial populations may modulate a successful infection process of the tick-borne pathogens. Therefore, there is a need to know the microbial population and their interactions. In this mini-review, we present several examples of how microbiota regulates the survival of pathogens inside the tick and contributes to fitness, adaptation, and tick immunity, among others. The communication between the tick microbiota and the host microbiota is vital to understanding the pathogen transmission process. As part of the tick microbiota, the pathogen interacts with different microbial populations, including the microorganisms of the host microbiota. These interactions comprise a microsystem that regulates the vectorial capacity involved in tick-borne diseases. The knowledge we have about the vectorial capacity contributes to a better understanding of tick-borne pathogens. Additionally, using approaches based on multi-omics strategies applied to studying the microbiota and its microbiome allows the development of strategies to control ticks. The results derived from those studies reveal the dynamics of the microbiota and potential targets for anti-tick vaccine development. In this context, the anti-microbiota vaccines have emerged as an alternative with a good prognosis. Some strategies developed to control other arthropods vectors, such as paratransgenesis, could control ticks and tick-borne diseases.
Highlights
Infectious diseases have been one of the main restrictions worldwide for animal production improvement, with significant economic losses
We show a general view of different approaches for studying the tick microbiota and other arthropod vectors, intending to integrate the current knowledge and present new alternatives for tick control
In this mini-review, we include recent results that show that the more knowledge and manipulation we have of the microbiota, we get closer to new vaccine development
Summary
Infectious diseases have been one of the main restrictions worldwide for animal production improvement, with significant economic losses. The main biological vectors of numerous infectious diseases (tick-borne diseases) [1,2,3] (Figure 1). The study of the tick microbiota and the biological processes in which it participates are still in progress to date, there is not enough information about its role in the vectorial capacity, infection, and pathogen transmission. This study opens up a research field to study and elucidate new targets for developing drugs/vaccines to prevent diseases that affect animals, including humans. Microbiota and Vectorial Capacity promising approach to control tick infestations. In this regard, the study of the tick microbiota contributes to elucidate the interactions that may be influencing vital processes and avoiding the transmission of pathogens [4, 5]. There is much work to obtain an effective drug or vaccine to control tick-borne diseases and the pathogens that cause them
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
