Abstract
Acute stress disorder (ASD) is a kind of mental disease caused by trauma, which will bring heavy burdens to patients themselves, their family, their work and their lives. Once a person who has suffered a trauma develops post-traumatic stress disorder (PTSD), the quality of life of patients will be overall impaired. It is found that the occurrence of stress disorder is related to the overactivation of hypothalamus pituitary adrenal axis (HPA axis). The most commonly used medications for ASD are recommended medications for PTSD, including serotonin reuptake inhibitors (SRIs), second-generation antipsychotics, benzodiazepines, beta blockers, and others. The purpose of this article is to systematically organize and review the possible mechanisms of stress disorder and drugs for treatment of ASD.
Highlights
Acute stress disorder (ASD), known as acute stress reaction (ASR), was proposed in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) in 1994
The duration of symptoms of ASD usually ranges from 3 days to 4 weeks after trauma, and when the duration of symptoms exceeds 4 weeks, it can be defined as post-traumatic stress disorder (PTSD)
Some researchers believe that the severity of early symptoms in post-traumatic patients is a major predictor of the risk of subsequent PTSD[8]
Summary
Acute stress disorder (ASD), known as acute stress reaction (ASR), was proposed in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) in 1994. The duration of symptoms of ASD usually ranges from 3 days to 4 weeks after trauma, and when the duration of symptoms exceeds 4 weeks, it can be defined as post-traumatic stress disorder (PTSD). ASD and PTSD are both stress disorders, and their symptoms and conditions can seriously affect individuals' social, occupational, interpersonal lives and physical health. They may cause significant economic burdens to individuals, families and society. A lot of ASD patients have been found to eventually develop PTSD[7]. Some researchers believe that the severity of early symptoms in post-traumatic patients is a major predictor of the risk of subsequent PTSD[8]. This paper summarized the advances in the pathogenesis and pharmacotherapy of ASD
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