Advances in the immune mechanisms of chronic rhinosinusitis

Abstract

Chronic rhinosinusitis (CRS) is a common disease of otolaryngology, which has a serious impact on the quality of life of patients. Its pathogenesis is complex and involves in allergic reactions, bacterial and fungal infections, immune dysfunction, impaired epithelial defense, environmental exposure and many other factors. In recent years, a raising attention has been paid to the role of immune mechanism in its pathogenesis; this article is a brief review aimes to the immune mechanism of chronic rhinosinusitis in recent years.