Abstract
The incidence of chronic pancreatitis (CP) is between 2 and 200 per 100,000 persons and shows an increasing trend year by year. India has the highest incidence of CP in the world at approximately 114 to 200 per 100,000 persons. The incidence of CP in China is approximately 13 per 100,000 persons. The aim of this review is to assist surgeons in managing patients with CP in surgical treatment. We conducted a PubMed search for “chronic pancreatitis” and “surgical treatment” and reviewed relevant articles. On the basis of our review of the literature, we found that CP cannot be completely cured. The purpose of surgical therapy for CP is to relieve symptoms, especially pain; to improve the patient’s quality of life; and to treat complications. Decompression (drainage), resection, neuroablation and decompression combined with resection are commonly used methods for the surgical treatment of CP. Before developing a surgical regimen, surgeons should comprehensively evaluate the patient’s clinical manifestations, auxiliary examination results and medical history to develop an individualized surgical treatment regimen.Electronic supplementary materialThe online version of this article (doi:10.1186/s12957-014-0430-4) contains supplementary material, which is available to authorized users.
Highlights
Chronic pancreatitis (CP) refers to limiting, segmental, diffusing, progressive inflammatory damage, necrosis, and interstitial fibrous lesions of pancreatic parenchyma caused by many different factors, usually accompanied by stenosis and dilation of the pancreatic duct, pancreatic calcification, and pancreatic stone formation
The necrosis of pancreatic acinar cells, the atrophy or loss of pancreatic islet cells, and extensive interstitial fibrosis will eventually result in the irreversible destruction of pancreatic morphology and structure as well as exocrine and endocrine pancreatic insufficiency
India has the highest incidence of CP in the world at approximately 114 to 200 per 100,000 persons [2]
Summary
Chronic pancreatitis (CP) refers to limiting, segmental, diffusing, progressive inflammatory damage, necrosis, and interstitial fibrous lesions of pancreatic parenchyma caused by many different factors, usually accompanied by stenosis and dilation of the pancreatic duct, pancreatic calcification, and pancreatic stone formation. The incidence of CP is between 2 and 200 per 100,000 persons and shows an increasing trend year by year [1,2]. India has the highest incidence of CP in the world at approximately 114 to 200 per 100,000 persons [2]. The incidence of CP in China is approximately 13 per 100,000 persons [1,2]. It has been reported that approximately 90% of patients with CP have symptoms of abdominal pain [3,4]. The mechanism of abdominal pain is still not clear, pancreatic duct
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