Abstract
Summary Signal amplified electrochemical (EC) biosensing has broad significance and practical values in the study of clinical medicine and genetic project. Using a variety of signal amplification strategies based on functional nanomaterials, enzyme catalysis, biological reactions, etc., one could effectively enhance biosensing response and reduce noise signals to detect trace number of analytes. To date, signal amplified EC biosensing has been widely used in the study of life science, biomedical research, food and environmental analysis, chemical analysis, etc. This review focuses on the advances during the last decade in the development and application of signal amplified EC , photoelectrochemical and electrochemiluminescence biosensing, using functional nanomaterials, enzyme catalysis and biological reactions. Perspectives of signal amplification strategies for EC biosensing are also addressed.
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