Abstract
Gonorrhea is a sexually transmitted disease caused by Neisseria gonorrhoeae infection. Its prevalence and spread have become a huge burden on global public health. Antimicrobial therapy is currently the main method for the prevention and treatment of gonorrhea. However, with the widespread use of antibacterial agents in clinical practice, the resistance of N. gonorrhoeae has become an increasingly serious problem. Exploration of the resistance mechanism of N. gonorrhoeae is essential for improving its resistance monitoring system and adjusting the antimicrobial treatment regimens. We reviewed the recent advances in research on the resistance mechanism of N. gonorrhoeae , aiming to provide reference for the prevention and treatment of gonorrhea in China.
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