Abstract
Rabies is fatal once clinical signs of severe rabies virus (RV) exposure are present.In order to replace rabies immune globulin from human and equine for postexposure prophylaxis of rabis,RV-neutralizing human monoclonal antibodies (mAb) have been investigated extensively.This review summarizes the therapoutic human mAb CR57 and its complementing mAb CR4098.Expresion systems of mAb are also discussed. Key words: Rabies virus; Antibodies; Monoclonal antibody CR57; Monoclonal antibody CR4098
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