Abstract

Convergence chromatography (CC) is a separation technique that utilizes both super and sub-critical carbon dioxide (CO2) and sub-2 μm stationary phases to achieve unique selectivity, low solvent usage and high efficiencies. The use of supercritical fluid as a mobile phase provides higher diffusivity and lower viscosity than liquid mobile phases, thereby providing higher throughput and chromatographic efficiencies as compared to liquid chromatography.

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