Abstract
Primary cutaneous marginal zone B-cell lymphoma (pcMZL) belongs to mucosa-associated lymphoid tissue (MALT) lymphoma, and is a subtype of indolent non-Hodgkin lymphoma. Chronic antigen stimulation and gene mutations are key-players in its pathogenesis. Biopsy and immunohistochemistry are gold-standard examination for the diagnosis and staging of pcMZL. The overall prognosis of patients is excellent. This review will illustrate the advances in pathogenesis, diagnosis, therapy and prognosis of pcMZL, aimed to raise the recognition and making choice of treatments for this disease. Key words: Lymphoma, B-cell, marginal zone; Antigens; Mutation; Therapeutics
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