Advances in pathogenesis and pharmacotherapy of cataract

Abstract

<p indent="0mm">Cataract is the leading cause of vision impairment worldwide. As the population ages, the prevalence of cataract will increase rapidly, which has caused a substantial social and economic burden. Although cataract surgery is effective, it still suffers from complications and high costs and could not meet the increasing surgery demand. Therefore, pharmacological treatment for cataracts is cheaper and more readily available for patients. Therefore, research on the pathogenesis of cataract and exploring potential therapeutic drugs for cataract have always been a research hotspot for years. Based on our team’s current work, this article summarizes the pathogenesis and pharmacotherapy strategies of cataract from the pathogenesis of cataract, the cataract disease models, and the development of anti-cataract drugs.