Abstract
When the three germ-layer theory was perfected by von Baer, it was thought that the fundamental parts concerned in the organization of our body tissues had been found and the ectoderm, mesoderm, and endoderm shown in his beautiful drawings were the three ultimate materials from which our various organs are derived, the three layers being regarded as homogenous in themselves and homologous in all animal forms. This concept seemed to simplify the teaching of embryology and during the subsequent hundred years embryologic and anatomic thought has been dominated by this three-layered topographic analysis, and with a certainty like that formerly prevailing among physicists and chemists regarding the indivisibility of the atom.
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