Abstract

It is clear from the amount of material in this book focused on various chromatographic techniques, that the analysis of complex hydrocarbon mixtures continues to be one of the biggest challenges facing analytical chemists in the pharmaceutical, biomedical, environmental, petroleum, polymer, and petrochemical arenas. Nuclear magnetic resonance (NMR) has long been recognised as the spectroscopic technique of choice for obtaining detailed structural, dynamic, and chemical information of organic compounds. However, the analysis of complex organic mixtures with traditional one-dimensional (1D) NMR techniques usually suffers from severe spectral overlap, making it virtually impossible to extract detailed compositional information. Many ingenious and elegant 1D, 2D, and multidimensional NMR spectral editing techniques have been developed that address various aspects of this resolution problem and are now routinely implemented on modern commercial spectrometers. Excellent texts describing both the theoretical aspects and the practical application of these techniques are available.1–5

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