Advances in Laser Ablation Synthesized Silicon-Based Nanomaterials for the Prevention of Bacterial Infection.

Marina Martínez-Carmona,María Vallet-Regí

doi:10.3390/nano10081443

Abstract

Nanomaterials have unique properties and characteristics derived from their shape and small size that are not present in bulk materials. If size and shape are decisive, the synthesis method used, which determines the above parameters, is equally important. Among the different nanomaterial’s synthesis methods, we can find chemical methods (microemulsion, sol-gel, hydrothermal treatments, etc.), physical methods (evaporation-condensation, laser treatment, etc.) and biosynthesis. Among all of them, the use of laser ablation that allows obtaining non-toxic nanomaterials (absence of foreign compounds) with a controlled 3D size, has emerged in recent years as a simple and versatile alternative for the synthesis of a wide variety of nanomaterials with numerous applications. This manuscript reviews the latest advances in the use of laser ablation for the synthesis of silicon-based nanomaterials, highlighting its usefulness in the prevention of bacterial infection.

Highlights

IntroductionAt a time in history when society looked “big” (bigger cars, bigger houses, bigger televisions, etc.) Richard Feynman turned back the tide and focused on the “small”
At a time in history when society looked “big” Richard Feynman turned back the tide and focused on the “small”
Most of the publications related to the use of Silicon-based nanomaterials synthesized by laser ablation for the treatment of infection focus on the creation of non-stick surfaces

Summary

Introduction

At a time in history when society looked “big” (bigger cars, bigger houses, bigger televisions, etc.) Richard Feynman turned back the tide and focused on the “small”. One of the main reasons is that silicon and silica nanomaterials have great mechanical resistance and thermal stability, which makes them ideal substrates for functionalization. This is a great advantage since it is precisely the possibility of anchoring a variety of elements on the surface of the nanomaterials, which allows modifying their properties depending on the necessary treatment. Considering the increasing demand for silicon-based nanomaterials in biomedical applications, new chemical free synthesis alternatives methods are being developed. Trfhaeceusl.trIat fhinase asilzsoe obfetehnepnraonpoopsaerdtitchleast twhaeshaigtthridbiuptoelde tmo othmeeDntMoSf Oorgoaxnidice sfoolrvmenattisocnasnognentheeraptearatisctlreosnugrefraceelesc. tIrtichadsoaulbsloeblaeyeenrpthroapt oensehdanthceast repulsive force between nanocrystals favoring the formation of smaller entities [76]

Effects of Laser Processing Parameters

Antibacterial Effect of Silicon-Based Nanomaterials

Findings

Conclusions and Future Perspectives