Abstract

Optic neuritis (ON) is an inflammatory demyelinating disorder of the optic nerve, which can be the first manifestation of multiple sclerosis (MS). In this paper we review the recent advances in early diagnosis of the disorder focusing primarily on the techniques : Retinal OCT Texture Analysis, Machine learning based on Color Fundus Images and Optical Coherence Tomography. This review is based on articles retrieved by a selective search of the PubMed database and other related journal articles, on the pertinent guidelines, and on the authors’ clinical experience. Throughout, we present tables that summarize and draw distinctions among key ideas and approaches. Where available, we provide comparative analyses, and we make suggestions for analyses yet to be done.

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