Advances in diagnostic and therapeutic colonoscopy

Abstract

We review current studies on endoscopic and technologic advances for the detection and treatment of colorectal neoplasia. Improvements in adenoma detection have been shown to be possible with the use of high definition white light as well as water-related methods such as water exchange. Use of cap assist colonoscopy, when combined with water-related methods, has recently been shown to also improve the detection of adenomas. Narrow band imaging and confocal laser endomicroscopy may have an advantage of offering endoscopists the ability to make an 'optical diagnosis' with the possibility of discarding nonadenomatous tissue. Furthermore, educational interventions aimed at improving adenoma detection may have lasting effects on endoscopists' adenoma detection rates. Lastly, endoscopic mucosal resection and endoscopic submucosal dissection are being applied for the treatment of large colorectal polyps, obviating the need for surgery in most instances. However, further studies are needed to establish the optimal methods for polyp resection. Advances in endoscopic technology are being shown to enhance the detection of early cancers and precancerous lesions. However, these tools may be supplementary to a high-quality colonoscopy using excellent techniques, factors that are now being implemented in training programs.