Abstract
The field of bioactive nanoparticles (NPs), also referred to as nanomaterials, has undergone significant growth and advancement in recent years. Synthetic and natural bioactive NPs are used in various applications, including wound healing, tissue engineering, and drug delivery. They have unique properties that make them ideal for biomedical applications, such as biocompatibility, biodegradability, and functionalizing with specific targeting moieties. Bioactive NPs have improved wound healing outcomes and reduced scar formation. Improved cell proliferation and differentiation in tissue engineering lead to the development of functional tissues. Moreover, NPs have improved targeted delivery and therapeutic efficacy in drug delivery. This review demonstrates how bioactive NPs have advanced in biomedical applications recently. Bioactive properties, green synthesis and fabrication techniques, bioactive wound healing mechanisms, tissue engineering, drug delivery, future directions, and challenges are also discussed in greater depth.
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