Advances in Alzheimer's disease research over the past two decades

Abstract

Over the past two decades, the landscape of dementia research has changed drastically due to advances in knowledge at the molecular, cellular, animal, and human levels. Advances have not been limited to the Alzheimer's disease spectrum but include improved understanding of other disorders that can also lead to dementia. In this Anniversary Round-up, I discuss what I consider to be the most important advances in Alzheimer's disease research that have occurred since the first publication of The Lancet Neurology 20 years ago. Dementia care: beyond a diagnosisEnormous progress has been made over the past two decades in dementia research. In particular, the identification of biomarkers is a landmark development in the diagnosis of Alzheimer's disease. However, this progress so far has not translated into improvements in patient care, with a staggering 85% of the over 55 million people living with dementia not receiving any post-diagnosis care, according to Alzheimer's Disease International's 2022 World Alzheimer Report . Full-Text PDF