Abstract
Optical coherence tomography angiography (OCTA) is the most relevant evolution based on optical coherence tomography (OCT). OCTA can present ocular vasculature, show detailed morphology for assessment, and quantify vessel parameters without intravenous dye agent. Research on the anterior segment OCTA (AS-OCTA) is only in its initial phase, and its advances in clinical diagnosis and treatment efficacy evaluations require a detailed comparison to traditional imaging methods. In this review of AS-OCTA, we summarize its technical features, imaging advances, current clinical applications in various eye diseases, as well as its limitations and potential future directions. AS-OCTA offers potential advantages in ophthalmic imaging, and with further development it could become a common tool in the near future.
Highlights
Optical coherence tomography (OCT) provides a non-invasive and rapid way to image the eye in vivo
The aim of this review is to summarize the current applications of the AS-Optical coherence tomography angiography (OCTA), including the diagnosis, therapy, and prognosis of detailed anterior diseases
The challenges in anterior segment OCTA (AS-OCTA) that were presented here should encourage the improvement of future techniques
Summary
Optical coherence tomography (OCT) provides a non-invasive and rapid way to image the eye in vivo. In the early 1990s, OCT was introduced to display retinal structures in cross-sections, such as the macula and optic nerve. OCTA allows better discrimination of the foveal avascular zone and parafoveal microvasculature than fluorescence angiography (FA), and can detect changes in lesions and early recurrence, even before the exudation detected on OCT [8,9,10,11,12]. OCTA has improved identification of capillary nonperfusion, microaneurysms, and retinal ischemia, as well as delineating the foveal avascular zone [11, 13,14,15,16,17,18,19,20,21,22]
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