Advancements in total knee arthroplasty kinematics: 3D implant computer aided design model creation through X-ray or fluoroscopic images

Abstract

Background3D-to-2D fluoroscopic registration is a popular and important step for analyzing total-knee-arthroplasty weight-bearing kinematics. Unfortunately, in vivo analyses using these techniques cannot be completed if the associated computer-aided design implant models are not available. This study introduces a novel method that enables the accessible computation of knee replacement patients' kinematics from fluoroscopy, achieved through the reconstruction of 3-dimensional knee component models using a limited set of 2-dimensional X-ray or fluoroscopic images. MethodsThe proposed non-rigid morphing algorithm, based on the coherent point drift algorithm, scales and transforms the shape of the template model to fit with the silhouette of the corresponding fluoroscopic images without changing the structure of the knee implant. While a greater number of fluoroscopic images can lead to higher accuracy, our study utilizes only 4 images. FindingsThe morphed models show excellent results in comparison with known models with a 0.52 mm average root-mean-square error and a 2.82 mm largest source error for 17 tested knee models of various implant types. The proposed algorithm also enables direct output of patient kinematics using fluoroscopy, with an average error of only 0.54 ± 0.42 mm for femorotibial contact and 0.86 ± 0.34 degrees for axial rotation. InterpretationA novel methodology was introduced to overcome common 3-dimentional to 2-dimensional registration limitations by recreating entire families of 3 dimensional models from a limited number of fluoroscopic images for both cruciate-retaining and posterior-stabilized knee replacement implants. Our algorithm has demonstrated high levels of accuracy with multiple potential extended applications.