Abstract

Simple SummaryWith the advancement of artificial intelligence, including machine learning, the field of oncology has seen promising results in cancer detection and classification, epigenetics, drug discovery, and prognostication. In this review, we describe what artificial intelligence is and its function, as well as comprehensively summarize its evolution and role in breast, colorectal, and central nervous system cancers. Understanding the origin and current accomplishments might be essential to improve the quality, accuracy, generalizability, cost-effectiveness, and reliability of artificial intelligence models that can be used in worldwide clinical practice. Students and researchers in the medical field will benefit from a deeper understanding of how to use integrative AI in oncology for innovation and research.Well-trained machine learning (ML) and artificial intelligence (AI) systems can provide clinicians with therapeutic assistance, potentially increasing efficiency and improving efficacy. ML has demonstrated high accuracy in oncology-related diagnostic imaging, including screening mammography interpretation, colon polyp detection, glioma classification, and grading. By utilizing ML techniques, the manual steps of detecting and segmenting lesions are greatly reduced. ML-based tumor imaging analysis is independent of the experience level of evaluating physicians, and the results are expected to be more standardized and accurate. One of the biggest challenges is its generalizability worldwide. The current detection and screening methods for colon polyps and breast cancer have a vast amount of data, so they are ideal areas for studying the global standardization of artificial intelligence. Central nervous system cancers are rare and have poor prognoses based on current management standards. ML offers the prospect of unraveling undiscovered features from routinely acquired neuroimaging for improving treatment planning, prognostication, monitoring, and response assessment of CNS tumors such as gliomas. By studying AI in such rare cancer types, standard management methods may be improved by augmenting personalized/precision medicine. This review aims to provide clinicians and medical researchers with a basic understanding of how ML works and its role in oncology, especially in breast cancer, colorectal cancer, and primary and metastatic brain cancer. Understanding AI basics, current achievements, and future challenges are crucial in advancing the use of AI in oncology.

Highlights

  • Artificial intelligence (AI) is a field in which computers are programmed to mimic human intelligence

  • This review article outlines how artificial intelligence (AI) works in simple terminology that medical professionals can understand, how it has improved breast cancer screening, colon polyp detection, and colorectal cancer screening, as well as the implications it has in the management of central nervous system (CNS) tumors

  • Computer systems are capable of learning tasks and predicting outcomes without being explicitly programmed through AI

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Summary

Introduction

Artificial intelligence (AI) is a field in which computers are programmed to mimic human intelligence. ML can be used to diagnose and classify tumors, detect early-stage tumors, gather genetic and histopathological data, assist in pre- and post-operative planning, and predict overall survival outcomes [1]. As a result of extensive data in present-day screening and improvements in life expectancy caused by early detection of breast and colon cancer, we review the potential of AI-based diagnostics and therapeutics. In the area of central nervous system (CNS) tumors, AI and radiomics have notably enhanced detection rates and reduced several time-consuming steps in glioma grading, pre- and intraoperative planning, and postoperative follow-up [13–15]. This review article outlines how AI works in simple terminology that medical professionals can understand, how it has improved breast cancer screening, colon polyp detection, and colorectal cancer screening, as well as the implications it has in the management of CNS tumors. We conclude with existing obstacles and future speculations of standardizing AI screening in oncology, as well as proposals for integrating AI basics into medical school curricula

How Does Artificial Intelligence Work?
Subtypes of Machine Learning
Deep Learning
Breast Cancer
Screening Mammogram
Genetics and Hormonal Aspects in Breast Cancer Prediction
Colonic Polyps and Colorectal Cancer
Colorectal Cancer Screening
Colonic Polyps Detection
Colon Polyps Classification
Histopathological Aspects, Genetics, and Molecular Marker Detection
Central Nervous System Cancers
Central Nervous System Neoplasm Detection
Radiomics
Intraoperative Modalities
Postoperative Surveillance
Precision and Personalized Medicine
AI Performance Interpretation
Standardization of Techniques
Bias in Artificial Intelligence
Ethical and Legal Perspectives
Integrative Training of Computer Science and Medical Professionals
Findings
Conclusions
Full Text
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