Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment

Abstract

Globally, Cancer therapy is still a major issue. With the latest developments in nanotechnology, layered double hydroxide (LDH)-based nanosystems are receiving special attention due to their pH dependent biodegradability, superior biocompatibility, easy surface modification, anion exchange capacity and high chemical stability, giving rise to great potential for cancer therapy. By intercalating inorganic, organic, or bio molecules into their lamellar lattice, new hybrid materials with dual or multi-functional features, including anticancer capabilities, can be developed from layered double hydroxide (LDH). Despite the fact that outstanding research has been published, few review papers address these essential and promising discoveries to stimulate the ongoing development of LDH-based nanosystems in the field of cancer therapy. This paper therefore study focuses on the most recent advancements in LDH-based chemotherapeutic nanosystems for cancer treatment. The information utilized in this review was gathered from studies that have previously been published and were retrieved from several Journal outlets. These reports dealt with the usage of layered doubled hydroxide-based chemotherapeutic nanosystems for the treatment of cancer. The research demonstrates that layered double hydroxides may be utilized to develop single or composite nanosystems that distribute therapeutic components precisely without causing cumulative damage for the field of nanomedicine.