Advancements in developing biomaterials for 3D printing photosensitive resins containing quaternary ammonium molecules for enhanced oral healthcare

Abstract

In this study, we investigated the development of biomaterials tailored for UV-cured 3D printing technology in oral healthcare. Traditionally, 3D-printed oral healthcare products have exhibited imperfections in antimicrobial and anti-pollution properties, limiting their utility. To address this challenge, we synthesised antimicrobial agents incorporating quaternary ammonium groups through a combination of isophorone diisocyanate (IPDI), hydroxyethyl methacrylate (HEMA), and choline chloride. These agents were then blended with diluents, resins, and photoinitiators to create raw materials suitable for UV-curing 3D printing photosensitive resins. Subsequently, the resins were subjected to digital light processing (DLP) 3D printing for curing. The resulting 3D-printed material underwent rigorous mechanical and antimicrobial testing. Our findings demonstrate that the 3D printed compounds, cured through this process, exhibited exceptional hardness, tensile properties, antimicrobial characteristics, and long-lasting antimicrobial durability. These developments promise widespread adoption and application within the oral healthcare field.